Method and apparatus for making nucleic acid arrays
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United States of America Patent
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Oct 1, 2002
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N/A
app pub date -
Sep 9, 1998
filing date -
Sep 9, 1998
priority date (Note) -
Expired
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Abstract
Methods and devices for depositing a nucleic acid on a substrate surface are provided. In the subject methods, a thermal inkjet head loaded with nucleic acid fluid composition is positioned in opposing relationship to, e.g. over, a substrate surface. Actuation of the thermal inkjet results in the expulsion of volume of the nucleic acid composition onto the substrate surface. The subject methods and devices find use in a variety of applications, particularly in the preparation of nucleic acid arrays, and more particular arrays of oligonucleotides or polynucleotides, e.g. cDNAs.
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