Solid preparation

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United States of America Patent

PATENT NO 6458824
SERIAL NO

09661577

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a solid preparation comprising a crystal of [3-[(2R)-[[(2R)-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1H-indol-7-yloxy]acetic acid (Compound A), especially a crystal of Compound A having a particle size of not larger than 100 .mu.m at the cumulative weight distribution value of 50%, and not larger than 200 .mu.m at the cumulative weight distribution value of 95%, preferably a solid preparation having the excellent stability and the content uniformity of Compound A, which is prepared by preparing granules of the crystal of Compound A with fillers, disintegrants and binders, and then followed by mixing said granules with external excipients.

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Patent Owner(s)

Patent OwnerAddress
DAINIPPON PHARMACEUTICAL CO LTDOSAKA JAPAN OSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujii, Akihito Ikoma, JP 17 143
Fujita, Megumi Otsu, JP 5 52
Fujiwara, Keiichi Kyoto, JP 11 59
Harada, Hiroshi Suita, JP 339 4451
Iwata, Motokazu Takatsuki, JP 3 105
Kato, Shiro Sakai, JP 57 1029
Kawashima, Hitoshi Osaka, JP 16 111
Kuriyama, Teruaki Higashiosaka, JP 3 15
Odai, Osamu Hirakata, JP 6 23

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