Compounds for the synthesis of nucleotide or oligonucleotide phosphoramidites

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Oct 1, 2002
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app pub date
Aug 27, 2001
filing date
Dec 16, 1997

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Expired

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Abstract

This invention presents novel methods for recovery of phophoramidites from the waste products of oligonucleotide synthesis. The methods include reacting a tribromophenoxydichlorophosphorane with an H-phosphonate in the presence of an amine.

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Patent Owner	Address
ISIS PHARMACEUTICALS INC	2280 FARADAY AVENUE CARLSBAD CA 92008 UNITED STATES OF AMERICA

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C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....

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Inventor Name	Address	# of filed Patents	Total Citations
Cole, Douglas L	San Diego, CA	192	1362
Griffey, Richard H	Vista, CA	162	5753
Ravikumar, Vasulinga	Carlsbad, CA	38	486

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Compounds for the synthesis of nucleotide or oligonucleotide phosphoramidites

Number of patents in Portfolio can not be more than 2000

United States of America Patent

09939881

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PATENT NO	6458941
SERIAL NO	09939881
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09939881

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