Microdialysis-probe integrated with a si-chip

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United States of America Patent

PATENT NO 6463312
SERIAL NO

09601873

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Microdialysis device (10), comprising at least a probe (1) provided with an inlet (2) and an outlet (3) for bringing a perfusion fluid into contact with a bodily fluid in a part of a living organism and causing constituents from this fluid to be taken up by this perfusion fluid, whereby the perfusion fluid is enriched to dialysate, wherein the outlet (3) is integrally received in a silicon chip (5) and debouches in a first fluid channel (6) formed in this silicon chip (5) and wherein further at least one analysis means, for instance an ISFET (17, 18), for analysing constituents of the bodily fluid taken up by the perfusion fluid is integrally received in the silicon chip (5) in a manner such that dialysate flowing from the outlet (3) comes into contact with said analysis means in the first fluid channel (6), and wherein the silicon chip (5) is further optionally provided with pumping means (50) or dosing means.

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Patent Owner(s)

Patent OwnerAddress
STICHTING VOOR FUNDAMENTEELPOSTBUS 3021 ONDERZOEK DER MATERIE NL-3502 GA UTRECHT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bergveld, Piet Haarboerhorst, NL 8 591
Bohm, Sebastian Gb Enschede, NL 149 8554
Olthuis, Wouter Gl Enschede, NL 7 92

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