Growth differentiation factor-8 nucleic acid and polypeptides from aquatic species and non-human transgenic aquatic species
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United States of America Patent
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Oct 15, 2002
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app pub date -
Aug 19, 1999
filing date -
Mar 19, 1993
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Abstract
A transgenic non-human aquatic organisms, such as piscine, crustacea, mollusks, and the like, having a transgene which results in disrupting the production of and/or activity of growth differentiation factor-8 (GDF-8) chromosomally integrated into the germ cells of the animal is disclosed. Also disclosed are methods for making such organisms and nucleic acid sequences encoding GDF-8 polypeptides from such aquatic organisms.
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