US Patent No: 6,471,660

Number of patents in Portfolio can not be more than 2000

Method and apparatus for measuring factors in mammary fluids

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Abstract

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Provided are methods for non-invasively obtaining mammary fluid from a subject. The method further provides methods for measuring the risk of a mammary disease by measuring a biological factor in the mammary fluid. Further provided is an apparatus useful in obtaining a mammary fluid from the mammary gland of a subject.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
WAYNE STATE UNIVERSITYDETROIT, MI237

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Covington, Chandice College of Nursing Center for Health Research 5557 Cass Ave., Detroit, MI 48202 5 65

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (9)
4,452,779 Composition and method of treating lactating mammals 24 1982
4,761,160 Human milk retrieval system 20 1987
5,576,329 Method for treating tendon or joint inflammation with papaverine HCL 10 1994
5,476,492 Body warmer for therapeutic purposes containing whole herb seed 28 1994
5,776,177 C-shaped heat pack for thermal treatment of breast 32 1995
5,628,964 Mastitis detecting device 12 1995
5,664,984 Brassiere having frontal moisture control 18 1996
5,902,267 Breast pump system using wall vacuum source 35 1997
5,913,686 Breast-mapping 21 1998
 
ATOSSA GENETICS, INC. (2)
5,798,266 Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer 39 1996
6,287,521 Methods and devices for obtaining and assaying mammary fluid samples for evaluating breast diseases, including cancer 99 1998
 
AVENT LIMITED (1)
5,885,246 Breast pump insert 62 1996
 
HARBOR-UCLA RESEARCH AND EDUCATION INSTITUTE (1)
5,895,640 Nuclear medicine techniques for detecting carcinoma in the dense breast 19 1996
 
Pigeon Co., Ltd. (1)
4,759,747 Breast pump including pressure adjusting means 62 1986
 
KIRCHNER & WLHELM (1)
4,583,970 Milk suction device 63 1985
 
DELAVAL INC. (2)
5,482,004 Collapsible teat liner with reinforced barrel 38 1994
5,493,995 Collapsing teat cup liner with tapering barrel wall 32 1994
 
WISCONSIN ALUMNI RESEARCH FOUNDATION (2)
5,627,034 Assay for carcinoma proliferative status by measuring NGAL expression level 20 1995
5,846,739 Immunohistochemical detection assay for carcinoma proliferative status 12 1997
 
GEORGETOWN UNIVERSITY (1)
6,316,189 Evaluation of changes in breast cells using nipple aspirate fluid 13 1998
 
THOMAS JEFFERSON UNIVERSITY (1)
2001/0039,015 Nipple aspirate fluid specific microarrays 15 2001
 
PRO DUCT HEALTH, INC. (1)
6,314,315 Ductal orifice identification by characteristic electrical signal 32 2000
 
ROSDEN COMPANY, A PARTNERSHIP (1)
4,542,750 Non-invasive method for diagnosing incipient or developed cancer tissue 16 1982
 
MICRO-MEDICAL DEVICES, INC. (1)
6,316,215 Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods 33 2000
 
MEDELA HOLDING AG (2)
5,941,847 Breast shield with vacuum isolation element 70 1998
6,004,186 Apparatus for securing suction devices to a nursing mother's breasts 41 1998
 
MATRITECH, INC. (1)
5,914,238 Materials and methods for detection of breast cancer 15 1996
 
MEDELA, INC. (4)
5,776,098 Diaphragm pump and pump mounted in a carrying case useful in breast pumping 60 1995
5,720,722 Connector for use in single and double breast pumping and breast pump using same 49 1996
5,797,875 Breast pump assembly and method of using same 29 1996
6,110,140 Manual breastmilk pump 43 1997
 
Advanced Cytometrix, Inc. (2)
5,645,537 Aspiration needle and syringe for use therewith, apparatus incorporating the same and kit for use in fine needle aspiration cytology, and method 23 1994
5,902,279 Aspiration needle and method 44 1995
 
CYTYC CORPORATION (3)
2002/0002,343 Devices, methods and systems for collecting material from a breast duct 12 2001
2002/0010,405 Devices, methods and systems for collecting material from a breast duct 11 2001
2002/0013,539 Methods and devices for diagnosis of precancer and cancer in breast milk ducts 18 2001
 
Agri-Automation Company, Ltd. (1)
4,941,433 Milking method and related apparatus 116 1988
 
ISG/AG, ALPENSTRASSE 2, CH-6300 ZUG, SWITZERLAND (1)
5,049,126 Breast pump with nipple stimulating insert 71 1990
 
ISG/AG (3)
5,007,899 Drive unit adapted for use with manual piston pump 102 1988
4,964,851 Battery-powered breastpump 73 1989
5,071,403 Method and apparatus for protecting the pump of a breast pump from fouling by milk 74 1989
 
University of Washington (3)
5,855,889 Mammaglobin, a mammary-specific breast cancer protein 28 1996
5,922,836 Mammaglobin antigens 31 1997
6,004,756 Method for detecting the presence of breast cancer by detecting an increase in mammaglobin mRNA expression 27 1998
 
Lact-Assist, Incorporated (1)
4,680,028 Flexible breast receptor for breast pump 72 1984
 
Ambic Group Limited (1)
4,376,053 Method and system employing a filter-detector for detecting mastitis in cows 33 1980
 
Brown; Bradley V. (1)
5,110,557 Blood sample collection apparatus 11 1990
 
Moore; Mae Lois (1)
4,393,811 Weighted teat cup shell and assembly 20 1981
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (1)
RE35316 Method for filtering a fluid sample using an in-line fluid filter for an automated analyzer 4 1992
 
KAO CORPORATION (1)
5,810,796 Absorbent article 27 1997
 
HISAMITSU PHARMACEUTICAL CO., INC. (1)
6,063,029 Diagnostic patch and method for diagnosis using the same 36 1996
 
Daikin Co., Ltd. (1)
5,741,649 Method and kit for detecting breast cancer cells 13 1996
 
Jex Co., Ltd. (1)
4,883,464 Milking equipment 56 1988
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 2005/0203,436 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue 28 2005
 
ATOSSA GENETICS, INC. (2)
* 6,887,210 Devices and methods for obtaining mammary fluid samples for evaluating breast diseases, including cancer 40 2001
* 6,689,073 Methods and devices for collecting, handling and processing mammary fluid samples for evaluating breast diseases, including cancer 20 2001
 
NEOMATRIX, LLC (1)
* 2008/0015,495 METHOD AND APPARATUS FOR NONINVASIVE INTRADUCTAL FLUID DIAGNOSTIC SCREEN 1 2007
 
EPI-SCI, LLC (14)
* 7,630,759 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium 8 2003
* 2004/0253,652 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium 19 2003
* 8,280,504 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue 2 2005
8,262,575 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue 1 2005
7,853,319 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium 3 2006
* 2006/0241,514 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium 13 2006
8,332,025 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium 2 2006
* 2008/0004,543 Electrophysiological approaches to assess resection and tumor ablation margins and responses to drug therapy 7 2007
* 2008/0009,764 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium 5 2007
8,738,124 Electrical bioimpedance analysis as a biomarker of breast density and/or breast cancer risk 0 2008
8,275,453 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium 2 2009
* 2010/0049,079 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium 0 2009
9,037,228 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue 0 2012
9,042,977 Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium 0 2012
 
HHC PREFERRED, LLC (3)
6,676,610 Disposable patient interface for intraductal fluid aspiration system 61 2002
7,468,043 Method and apparatus for noninvasive intraductal fluid diagnositc screen 14 2005
* 2005/0171,471 Method and apparatus for noninvasive intraductal fluid diagnostic screen 1 2005
 
HALO HEALTHCARE, INC. (1)
* 2003/0073,951 Disposable patient interface for intraductal fluid aspiration system 13 2002
 
Neo Matrix, LLC (1)
7,575,557 Disposable fluid loop for intraductal fluid aspiration system 40 2002
 
NOEMATRIX, LLC (2)
6,899,696 Method of noninvasively obtaining intraductal fluid 21 2004
* 2004/0181,205 Method of noninvasively obtaining intraductal fluid 4 2004
 
IWS, INGENIEURGESELLSCHAFT WEINTER & SCHROTER MBH (1)
* 2005/0012,361 Protective door for drivers' cabins, in particular for utillity vehicles 0 2002
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
* 6,855,554 Methods and compositions for detection of breast cancer 10 2002
 
NEW YORK UNIVERSITY (1)
* 2004/0178,162 Devices and methods for removal of leukocytes from breast milk 4 2004
* Cited By Examiner