Biocompatible prosthetic tissue

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6471723
SERIAL NO

09480437

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Abstract

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Crosslinked tissue is contacted with one or more toxicity reducing solutions to remove cytotoxicity associated with the crosslinking process. In particular, crosslinked tissue can be contacted with an inorganic sulfur-oxygen group to form chemical adducts of aldehydes and the inorganic sulfur-oxygen group. Preferably, the cytotoxicity reduced crosslinked tissue has no residual cytotoxicity. In preferred embodiments, a plurality of toxicity reducing agents are used to detoxify the tissue. Preferred toxicity reducing agents include, for example, inorganic sulfur-oxygen ions, such as bisulfate and thiosulfate, organic sulfates, amines, ammonia/ammonium, and surfactants.

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Patent Owner(s)

Patent OwnerAddress
ST JUDE MEDICAL INCONE LILLEHEI PLAZA ST PAUL MN 551179913

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashworth, Paul Edward Andover, MN 11 1449
Johnson, Andrea L Fridley, MN 3 194
Kelly, Sheila Jeanne Vadnais Heights, MN 2 178
McTavish, Daniel Paul Fridley, MN 2 178
Ogle, Matthew Frank St. Paul, MN 3 192

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