Using polyamide nucleic acid oligomers to engender a biological response

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United States of America Patent

PATENT NO 6472209
SERIAL NO

08953269

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention involves methods and materials for extracellularly administering PNA oligomers to living cells. Specifically, the invention provides methods of treating living cells with PNA oligomers such that the oligomers cross biological barriers and engender a biological response in a sequence specific manner. This invention also provides methods of screening potential PNA oligomers for the ability to engender a sequence specific biological response. Further, this invention provides methods of identifying the function of polypeptides and of determining the relative turnover rate of functional polypeptides.

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Patent Owner(s)

  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cusack, Bernadette Marie Jacksonville Beach, FL 15 58
Douglas, Christopher Lee Jacksonville, FL 5 4
Hoshall, Clark V Ponte Vedra Beach, FL 3 3
Jansen, Karen Jacksonville, FL 5 4
McCormick, Daniel J Rochester, MN 28 127
Richelson, Elliott Ponte Vedra Beach, FL 40 89
Tyler, Beth Marie Neptune Beach, FL 15 53

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