Methods, kits and compositions pertaining to linear beacons
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United States of America Patent
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Nov 26, 2002
Grant Date -
N/A
app pub date -
Oct 26, 1998
filing date -
Oct 27, 1997
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Abstract
This invention is directed to methods, kits and compositions pertaining to Linear Beacons. In the absence of a target sequence, Linear Beacons facilitate efficient energy transfer between the donor and acceptor moieties linked to opposite ends of the probe. Upon hybridization of the probe to a target sequence, there is a measurable change in at least one property of at least one donor or acceptor moiety of the probe which can be used to detect, identify or quantitate the target sequence in a sample.
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