Production of lactate using crabtree negative organisms in varying culture conditions

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United States of America Patent

PATENT NO 6485947
SERIAL NO

09574873

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Abstract

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Crabtree negative organisms such as Kluyveromyces, Pichia, Hansenula and Candida, are used to make selected organic products such as lactic acid. The organisms are cultured in a first culture medium that includes glucose, under conditions that promote cellular respiration. The organisms are then cultured under a second set of conditions that promote production of the selected organic product. The organisms preferably contain an exogenous lactate dehydrogenase gene.

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Patent Owner(s)

Patent OwnerAddress
CARGILL INCP O BOX 5624 LAW DEPARTMENT MS 24 MINNEAPOLIS MN 55440-5624

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carlson, Ting Dayton, OH 3 202
Eyal, Aharon Jerusalem, IL 102 1312
Hatzimanikatis, Vassily Minneapolis, MN 3 202
Kolstad, Jeffrey J Wayzata, MN 48 3044
Olson, Stacey Minneapolis, MN 10 254
Rajgarhia, Vineet Minnetonka, MN 31 502
Starr, John N Chaska, MN 10 456

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