Anti-CCR4 antibodies and methods of use therefor
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United States of America Patent
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Dec 3, 2002
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app pub date -
Jan 15, 1999
filing date -
Jan 15, 1999
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Abstract
The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 4 (CCR4) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR4 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
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