Method of DNA shuffling
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United States of America Patent
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Dec 3, 2002
Issued Date -
N/A
app pub date -
Oct 31, 1997
filing date -
Jul 9, 1996
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Abstract
Disclosed is a method of producing random polynucleotides by introducing two or more related polynucleotides into a suitable host cell such that a hybrid polynucleotide is generated by recombination and reductive reassortment. Also provided are vector and expression vehicles including such polynucleotides, polypeptides expressed by the hybrid polynucleotides and a method for screening for hybrid polypeptides.
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