Susceptibility mutation 6495delGC of BRCA2
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United States of America Patent
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Dec 10, 2002
Grant Date -
N/A
app pub date -
Sep 21, 1998
filing date -
Sep 23, 1997
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A new mutation has been found in the BRCA2 gene. The mutation is a twobase pair deletion of nucleotide 6495 at nucleotides 6495 of the published cDNA sequence of BRCA2. A process for identifying a sequence variation in a BRCA2 polynucleotide sequence is disclosed. The identification process includes allele specific sequence-based techniques assays of known sequence variations. The methods can be used for efficient and accurate detection of a mutation in a test BRCA2 gene sample.
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