Method of making a fibrin sealant comprising alpha-2-antiplasmin
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United States of America Patent
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Dec 10, 2002
Grant Date -
N/A
app pub date -
Dec 9, 1998
filing date -
Dec 9, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides a kit for preparing a fibrin sealant either (A) comprising: (a) a fibrin monomer preparation; (b) a stabilizing preparation containing a clot-preserving effective amount of a fibrinolysis-inhibiting protein; and (c) a non-enzymatic polymerizing agent preparation effective to convert the fibrin monomer preparation into a fibrin clot; or (B) comprising: (a') a fibrin monomer preparation comprising a fibrin monomer and a clot-preserving effective amount of a of a fibrinolysis-inhibiting protein; and (c') a polymerizing agent preparation effective to convert the fibrin monomer preparation into a fibrin clot.
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