Method for administering camptothecins via injection of a pharmaceutical composition comprising microdroplets containing a camptothecin

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United States of America Patent

PATENT NO 6497896
APP PUB NO 20020147202A1
SERIAL NO

09782182

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Abstract

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A method for administering a camptothecin to a patient comprising: injecting into a patient a pharmaceutical composition comprising an aqueous suspension of microdroplets suitable for intravenous delivery, the microdroplets having a mean diameter between 200 Angstroms and one micron, the microdroplets comprising a substantially water-insoluble, pharmacologically acceptable liquid, a camptothecin dissolved in the water-insoluble, pharmacologically acceptable liquid, and an outer layer comprising a phospholipid. The pharmaceutical composition is particularly well suited for delivering camptothecins, particularly 9-nitro-camptothecin intravenously.

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Patent Owner(s)

Patent OwnerAddress
ROYALTY SECURITIZATION TRUST I50 CALIFORNIA STREET SUITE 300 C/O PAUL CAPITAL ADVISORS L L C (AS ADMINISTRATOR) SAN FRANCISCO CA 94111

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mishra, Awadhesh Verdun, CA 6 427
Sands, Howard Wilmington, DE 8 181

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