Methods of identifying agents that modulate the binding between MDC and an MDC receptor

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United States of America Patent

PATENT NO 6498015
SERIAL NO

08939107

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Abstract

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The present invention provides purified and isolated polynucleotide sequences encoding a novel human macrophage-derived C-C chemokine designated Macrophage Derived Chemokine (MDC), and polypeptide analogs thereof. Also provided are materials and methods for the recombinant production of the chemokine, and purified and isolated chemokine protein, and polypeptide analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing.

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Patent Owner(s)

Patent OwnerAddress
ICOS CORPORATION A DELAWARE CORPORATION22021 20TH AVENUE SE BOTHELL WA 98021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Godiska, Ronald Verona, WI 18 153
Gray, Patrick W Seattle, WA 43 775
Raport, Carol J Bothell, WA 11 144

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