Methods and compositions for chromosome 21-specific staining
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United States of America Patent
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Dec 31, 2002
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jan 16, 1986
priority date (Note) -
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Abstract
Methods and compositions for chromosome-specific staining are provided. Composition comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.
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