Compensation of human variability in pulse oximetry
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United States of America Patent
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Dec 31, 2002
Grant Date -
Sep 19, 2002
app pub date -
Jan 22, 2001
filing date -
Jan 22, 2001
priority date (Note) -
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Abstract
The invention relates to the calibration of a pulse oximeter intended for non-invasively determining the amount of at least two light absorbing substances in the blood of a subject. In order to take human variability into account, the calibration is based on an invariant which is a quotient of two pseudo-isobestic signals. Each pseudo-isobestic signal is a weighted sum of two signals, and the weighted sum is theoretically independent of the relative concentrations of said substances in the blood of the subject. By using theoretical values of the invariant on the one hand, and values based on in-vivo measurements on the other hand, the calibration curve of the pulse oximeter is adapted to the characteristics of each individual patient.
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