Terminally sterilized osteogenic devices and preparation thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6504079
APP PUB NO 20020106394A1
SERIAL NO

09954748

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are terminally sterilized osteogenic devices for implantation into a mammal. The devices contain a combination of a biologically active osteogenic protein and an insoluble carrier which after being combined are sterilized by exposure to ionizing radiation, for example, by exposure to gamma rays or an electron beam. The terminally sterilized devices of the invention are characterized in that they induce bone formation following implantation into a mammal. Also disclosed is a method for inducing bone formation in a mammal by implanting a terminally sterilized device of the invention into a preselected locus in a mammal. Also disclosed is a method for preparing the terminally sterilized device of the invention.

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Patent Owner(s)

Patent OwnerAddress
MARIEL THERAPEUTICS INC135 E 57TH STREET 24TH FLOOR NEW YORK NY 10022

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rueger, David C Southborough, MA 109 3184
Sampath, Kuber T Holliston, MA 60 923
Tucker, Marjorie M Holliston, MA 14 671

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