Benzazepinone-derivatives

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United States of America Patent

PATENT NO 6506744
SERIAL NO

09611700

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Abstract

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Compounds of formula I ##STR1## as well as pharmaceutically usable salts and esters thereof, inhibit the binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. They can be used in the form of pharmaceutical preparations for the treatment or prevention of neoplasms, tumor metastasis, tumor growth, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, fibrosis, kidney failure as well as infection caused by viruses, bacteria or fungi.

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Patent Owner(s)

Patent OwnerAddress
HOFFMANN-LA ROCHE INC150 CLOVE ROAD OVERLOOK AT GREAT NOTCH SUITE 8 LITTLE FALLS NJ 07424

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alig, Leo Magden, CH 42 607
Chucholowski, Alexander Grenzach-Wyhlen, DE 33 351
Weller, Thomas Basel, CH 137 1583

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