Implantable bioartificial active secretion system
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United States of America Patent
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Jan 28, 2003
Issued Date -
N/A
app pub date -
Jan 30, 2001
filing date -
Jan 30, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An implantable bioartificial active secretion system for providing a physiological secretion such as insulin necessary for functionality of a physiologic activity such as glucose metabolism of a living-being host. The system includes a housing implantable within the host in fluidic communication with tissue fluid indicative of secretion need. A chamber within the housing contains a plurality of physiologically active, autonomously functioning, live secretory cells for producing the physiological secretion. A periodically operating pump apparatus moves tissue fluid into contact with the secretory cells for pick up of the regulating physiological secretion for subsequent physiologically-effective dispensing into the host while avoiding immunorejection of the host body or of the host to the secretory cells.
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