Microcapsules for administration of neuroactive agents
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United States of America Patent
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Feb 11, 2003
Issued Date -
N/A
app pub date -
Jun 29, 1994
filing date -
May 16, 1990
priority date (Note) -
Expired
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Abstract
The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient. Microspheres of less than 45 .mu.m, preferably less than about 20 .mu.m, and preferably about 0.1 .mu.m to about 10 .mu.m in mean diameter according to the present invention are also selectively taken-up and into astrocytes when delivered directly into the nervous tissues.
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