Methods and computer program products for determining risk of developing type 2 diabetes and other insulin resistance related disorders

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United States of America Patent

PATENT NO 6518069
SERIAL NO

09550359

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods for assessing the risk of developing Type 2 diabetes and other related disorders include obtaining an NMR derived reference spectrum for a known glucose concentration sample and storing this information as a reference standard. A patient blood sample is collected and NMR derived patient spectrums for the blood sample are obtained. The two NMR data sets (the reference and the patient) are compared and a glucose concentration is determined for the patient sample. The glucose concentration can be evaluated with a blood sample undergoing lipoprotein cholesterol evaluation. The NMR based test can be used to concurrently provide a glucose concentration and lipoprotein constituent values based on a single testing event. The disclosure also includes a multi-purpose test, i.e., a test which concurrently provides lipoprotein screening and coronary heart disease risk evaluation along with a diabetes screening and risk assessment for developing Type 2 diabetes. A method for assessing diabetes includes identifying the presence of diabetic dyslipidemia based on the values of predetermined NMR measured lipoprotein constituents.

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Patent Owner(s)

Patent OwnerAddress
LABORATORY CORPORATION OF AMERICA HOLDINGS358 SOUTH MAIN STREET BURLINGTON NC 27215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Dennis W Shorewood, WI 17 133
Otvos, James D Apex, NC 50 627

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