Ionic chitosan -iodine complexes: antiseptic hydrogels and wound healing promoters
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United States of America Patent
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Feb 18, 2003
Grant Date -
Aug 29, 2002
app pub date -
Dec 22, 2000
filing date -
Dec 22, 2000
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Abstract
This invention describes non-staining, pharmaceutically useful compositions of ionic complexes made between the cationic polymer chitosan or its derivatives and the small anionic iodine-iodide complex (ICIC's). Unlike previously disclosed ion transfer chitosan iodine complexes, ICIC's were found to possess dramatically higher viscosity than those of each ingredient separately, and instantly form a gel structure that is easily dispersible upon shaking. In addition to their antiseptic power, ICIC's showed better skin biocompatibility than povidone iodine and effectively promoted wound healing.
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