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Abstract

Cardiac performance associated pacing parameters is improved by applying evolutionary algorithms that maintain a plurality of sets of pacing parameters for pacing a heart. An initial plurality of sets of pacing parameters are determined. A cardiac performance value is determined for each of the plurality of sets of pacing parameters. At least one set of pacing parameters is selected from the plurality of sets of pacing parameters based on the cardiac performance values. An updated plurality of sets of pacing parameters is then created based on the selected at least one set of pacing parameters. These steps (except for determining the initial plurality of sets of pacing parameters) are repeating a plurality of times, wherein each time the steps are repeated, the updated plurality of sets of pacing parameters most recently created are used. During performance of the above described steps the heart will be paced according to a plurality of different sets of pacing parameters that should all eventually evolve toward and be close to an optimum set of pacing parameters.

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