Enhancement of oligomeric viral immunogenicity
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United States of America Patent
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Feb 25, 2003
Grant Date -
Nov 21, 2002
app pub date -
May 18, 2001
filing date -
May 18, 2001
priority date (Note) -
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Abstract
A method and structure for forming a viral-physiological structure. A naked virus having a capsid is provided. A linker molecule having a covalently attached polymer is covalently bonded to the capsid to form a polymer-protected virus. An immunogenicity of the polymer-protected virus with respect to an animal exceeds an immunogenicity of the naked virus with respect to the animal.
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