Cyclodextrins preferentially substituted on their primary face by acid or amine functions
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United States of America Patent
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Feb 25, 2003
Grant Date -
N/A
app pub date -
Jul 11, 2000
filing date -
May 12, 2000
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Abstract
Non-hydroxyalkylated cyclodextrins are disclosed wherein at least one primary alcohol function (CH.sub.2 OH) is substituted, the --OH portion being replaced by a substituent with formula --O--CO--R or --NR.sub.1 R.sub.2, where: R, R.sub.1 and R.sub.2 independently represent a linear or cyclic, saturated or unsaturated, hydroxylated or non-hydroxylated alkyl group containing 1 to 30 carbon atoms, preferably 1 to 22 carbon atoms, more preferably a fatty chain containing 2 to 22 carbon atoms. These cyclodextrins are used as vectors for at least one active ingredient, in particular to encourage tissue penetration, in a cosmetic application, or for the production of pharmaceutical compositions, in particular dermopharmaceuticals.
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