US Patent No: 6,525,024
Number of patents in Portfolio can not be more than 2000
Inhibitors of the ICE/ced-3 family of cysteine proteases
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Feb 25, 2003
Issued date -
Apr 17, 2001
filing date -
09/837,614
serial no -
Expired
status
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Abstract
This invention is directed to novel sulfonimide (substituted)acyl dipeptidyl ICE/ced-3 family inhibitor compounds having the following structure: ##STR1## wherein A, B, X, R, R.sup.1, R.sup.2, n, q, and r are as defined herein. The invention is also directed to pharmaceutical compositions containing these compounds, as well as the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
|---|---|---|---|
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| 5,714,484 .alpha.-(1,3-dicarbonylenol ether) methyl ketones as cysteine protease inhibitors | 6 | 1995 | |
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| 5,656,627 Inhibitors of interleukin-1.beta. converting enzyme | 57 | 1995 | |
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| 5,919,790 Hydroxamate inhibitors of interleukin-1.beta. converting enzyme | 23 | 1997 | |
Patent Citation Ranking
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| Fee | Large entity fee | small entity fee | micro entity fee | due date |
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| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Aug 25, 2014 |
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