Purines and pyrimidines linked to a quencher

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United States of America Patent

PATENT NO 6531581
SERIAL NO

09646669

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Abstract

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Compounds are described comprising purines substituted at the C-8 position and pyrimidines substituted at the C-4 position with a linker and quencher. These compounds, when incorporated into hairpin oligonucleotides quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide. These nucleotide-quencher compounds are also easily incorporated into oligonucleotides using conventional or automated oligonucleotide synthetic techniques.

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Patent Owner(s)

Patent OwnerAddress
EMD MILLIPORE CORPORATION290 CONCORD ROAD BILLERICA MA 01821

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boal, Jila McLean, VA 2 114
Nardone, Glenn Oakton, VA 3 120
Nazarenko, Irena Gaithersburg, MD 2 114

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