Cardiac function comprising implantation of embryonic stem cell in which differentiation has been initiated
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United States of America Patent
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Mar 18, 2003
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N/A
app pub date -
Sep 5, 2000
filing date -
Sep 5, 2000
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Expired
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Abstract
The present invention is a method for markedly improving cardiac function and repairing heart tissue in a living mammalian subject after the occurrence of a myocardial infarction. The method is a surgical technique which introduces and implants mammalian embryonic stem cells into the infarcted area of the myocardium. After implantation, the embryonic stem cells form stable grafts and survive indefinitely within the infarcted area of the heart in the living host. The demonstrated beneficial effects of the method include a decreased infarcted area and improved cardiac function as assessed by hemodynamic and echocardiographic measurements.
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