Guanidinium functionalized oligonucleotides and method/synthesis

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United States of America Patent

PATENT NO 6534639
SERIAL NO

09612531

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Abstract

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The present invention provides oligomers which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligomer is modified to include a guanidinium group. These oligomers are useful for diagnostic, therapeutic and investigative purposes.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INC2280 FARADAY AVENUE CARLSBAD CA 92008 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cook, Phillip Dan Fallbrook, CA 180 11137
Manoharan, Muthiah Carlsbad, CA 491 18658
Mohan, Venkatraman Carlsbad, CA 21 495
Prakash, Thazha P Carlsbad, CA 184 5389

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