Methods and compositions to alter the cell surface expression of phosphatidylserine and other clot-promoting plasma membrane phospholipids
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United States of America Patent
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Mar 18, 2003
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N/A
app pub date -
Aug 16, 1999
filing date -
Apr 2, 1996
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Abstract
A protein preparation that mediates Ca.sup.+2 transbilayer movement of phospholipid is disclosed. Additionally, a modified or mutated protein preparation, wherein the protein has a reduced ability to mediate transbilayer movement, is disclosed. In a preferred form of the invention, the protein has been modified such that post-translational modification can no longer occur.
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