Protein separation via multidimensional electrophoresis
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United States of America Patent
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Mar 25, 2003
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N/A
app pub date -
Feb 25, 2000
filing date -
Feb 24, 1998
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Expired
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Abstract
The present method provides methods and apparatus for separating proteins using a series of electrophoretic methods that utilize controlled fractionation and labeling techniques to resolve mixtures of proteins. The samples for each electrophoretic method other than the initial method, contain only a subset of proteins resolved in the preceding method. The methods can be used in a variety of different applications including, creating proteomic databases, comparative expression studies, diagnostics, structure activity relationships and metabolic engineering investigations.
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