Gene involved in cadasil, method of diagnosis and therapeutic application

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United States of America Patent

PATENT NO 6537775
SERIAL NO

09230652

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)101 RUE DE TOLBIAC PARIS 75013
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS3 AVENUE VICTORIA PARIS 75004

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bach, Jean-Francedillaois Paris, FR 1 45
Bousser, Marie-Germaine Paris, FR 3 45
Joutel, Anne Paris, FR 5 79
Tournier-Lasserve, Elisabeth Paris, FR 4 45

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