Use of nerve growth factor for the storage, culture or treatment of cornea
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United States of America Patent
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Mar 25, 2003
Grant Date -
Mar 28, 2002
app pub date -
Oct 25, 1999
filing date -
Apr 24, 1997
priority date (Note) -
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Abstract
The nerve growth factor (NGF) is used for the storage of corneas in culture, for the production and the storage in vitro of single cell populations of the corneal morphological and functional unit (i.e., epithelium, stroma/keratocytes and endothelium) and of the conjunctival epithelium, and for the production and the storage of corneal and conjunctival tissues, in particular for transplantation purposes. The NGF is also proposed for use in the therapy and/or the prophylaxis of diseases of the corneal surface, wherein a lack of integrity of the corneal and conjunctival morphological and functional unit occurs, in particular for pathologies having a dystrophic or neurodystrophic basis, both congenital and acquired.
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