Compositions and methods for altering the biodistribution of biological agents
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United States of America Patent
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Mar 25, 2003
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N/A
app pub date -
Jun 9, 2000
filing date -
Jun 28, 1996
priority date (Note) -
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Abstract
The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a therapeutic or diagnostic substance. This can allow for lower doses and for improved efficacy with drugs which traditionally reach targeted sites and can result in improved utility for agents such as oligonucleotides and polynucleotides which are plagued with problems with biodistribution.
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