Paclitaxel formulation
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United States of America Patent
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Mar 25, 2003
Grant Date -
Aug 1, 2002
app pub date -
Sep 5, 2001
filing date -
Oct 25, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: paclitaxel, a water-miscible amide and a pharmaceutically-acceptable, water-miscible solubilizer selected from the group consisting of solubilizers having the general structures R.sub.1 COOR.sub.2, R.sub.1 CONR.sub.2, and R.sub.1 COR.sub.2, wherein R.sub.1 is a hydrophobic C3-C50 alkane, alkene or alkyne and R.sub.2 is a hydrophilic moiety.
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