Stabilization of cardiac troponin I subunits and complexes
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United States of America Patent
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Mar 25, 2003
Grant Date -
Dec 19, 2002
app pub date -
Apr 27, 2001
filing date -
Apr 27, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides methods for preparing, and compositions comprising, stabilized protein-polymer conjugates. More particularly, the present invention relates to the stabilization of individual and complexed subunits of multisubunit protein complexes by conjugation to polymers. Such conjugation acts to stabilize the specific subunit complexes in their native conformation in liquid medium.
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