Polypeptide variants

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United States of America Patent

PATENT NO 6538124
SERIAL NO

09680145

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Abstract

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Isolated nucleic acid, vectors and host cells encoding antibody or immunoadhesin variants, as well as a process for producing the variants. The variants comprise a human IgG Fc region with amino acid substitution(s) therein, and display altered C1q binding function.

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Patent Owner(s)

Patent OwnerAddress
GENENTECH INC1 DNA WAY SOUTH SAN FRANCISCO CA 94080-4990

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Idusogie, Esohe Ekinaduese Burlingame, CA 7 2318
Mulkerrin, Michael George Hillsborough, CA 7 2318
Presta, Leonard G San Francisco, CA 238 16543

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