Importance

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Abstract

A highly safe medical device which exhibits long-lasting low surface friction in a body fluid or in an aqueous medium is provided. Also provided is a method for producing such medical device wherein substantially no limitation is imposed on the type of the substrate used, and the hydrophilic high molecular weight compound or the water-soluble or water-swellable high molecular weight compound responsible for the surface lubricity can be readily coated on the surface. In the present invention, a hydrophilic high molecular weight compound having at least one carbonyl group or hydrazine residue in the molecule and a cross-linking agent having at least two hydrazine residues or carbonyl groups in the molecule are reacted to thereby form a surface lubrication layer comprising the reaction product. In another embodiment, an interpenetrating network is formed between the reaction product of a compound having at least one carbonyl group or hydrazine residue in the molecule and a cross-linking agent, and a water-soluble or water-swellable high molecular weight compound to thereby form a surface lubrication layer.

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First Claim