Porous synthetic vascular grafts with oriented ingrowth channels
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United States of America Patent
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Apr 1, 2003
Grant Date -
N/A
app pub date -
Nov 5, 1999
filing date -
Nov 23, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.
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