Process for making optically active .alpha.-amino ketones and selected novel optically active .alpha.-amino ketones

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6541654
APP PUB NO 20020049332A1
SERIAL NO

09973990

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention includes selected novel optically active .alpha.-amino ketones which either are themselves useful or are intermediates for the preparation of known ketomethylene pseudopeptides useful as antibiotics, antibiotic enhancers, or enzyme inhibitors. Further, the present invention provides a method for dehydrogenation/asymmetrical hydrogenation to obtain essentially pure antipodes of ketomethylene pseudopeptides having two chiral centers.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MONSANTO COMPANYST LOUIS, MO294

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Talley, John J Chesterfield, MO 230 2266

Cited Art Landscape

Patent Info (Count) # Cites Year
 
TAKASAGO INTERNATIONAL CORPORATION (2)
4916252 Process for preparing optically active alcohol 18 1988
4906773 Process for preparing optically active threonine 10 1988
 
OCCIDENTAL CHEMICAL CORPORATION (1)
4912221 Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof 15 1988
 
MONSANTO COMPANY (3)
4939288 Method of preparing (R)-succinic acid derivatives 28 1989
5364961 Process for making optically active .alpha.-amino ketones 4 1992
5488132 Process for making optically active alpha-amino ketones and selected novel optically active alpha-amino ketones 4 1994
 
HOFFMANN-LA ROCHE INC. (1)
4316847 Pyrroles and pyrrolidines 13 1980
 
WASHINGTON UNIVERSITY (1)
5086165 Inhibitors of retroviral protease with a ketomethylene isosteric replaced amide bond 23 1991
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
MONSANTO COMPANY (1)
* 6849756 Process for making optically active .alpha.-amino ketones and selected novel optically active .alpha.-amino ketones 0 2003
 
PHARMACIA CORPORATION (1)
7211686 Process for making optically active .alpha.-amino ketones and selected novel optically active .alpha.-amino ketones 0 2005
* Cited By Examiner