Nucleic acid ligand diagnostic biochip
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United States of America Patent
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Apr 8, 2003
Issued Date -
N/A
app pub date -
Aug 14, 2000
filing date -
Dec 15, 1997
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Abstract
A diagnostic biochip comprising a solid support to which one or more specific nucleic acid ligands is attached in a spatially defined manner is provided. Each nucleic acid ligand binds specifically and avidly to a particular target molecule contained within a test mixture, such as a bodily fluid. Also provided are methods for the preparation of nucleic acid ligand biochips. Further, methods for the use of the nucleic acid ligand biochip in diagnosis of a medical condition and quantitative detection of a target molecule are provided.
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