Catechols as antimicrobial agents
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United States of America Patent
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Apr 8, 2003
Grant Date -
Apr 4, 2002
app pub date -
Aug 22, 2001
filing date -
May 5, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Compounds, pharmaceutically acceptable salts, and compositions thereof of the general formula: ##STR1## wherein Ar is aryl and heteroaryl; R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are hydrido, alkyl, cyano, heteroaryl, hydroxy, amino, acylamino, halo, alkoxy, aryloxy, carboxyamido, alkenyl, cycloalkyl, heterocyclyl, acyl, acyloxy, carboalkoxy, carboxy, thio, sulfinyl, sulfonyl and sulfoxy, R.sup.5, R.sup.6, R.sup.7, and R.sup.8 are hydrido and lower alkyl; and Het is a nitrogen-containing heterocyclic ring.
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