US Patent No: 6,546,927

Number of patents in Portfolio can not be more than 2000

Methods and apparatus for controlling piezoelectric vibration

ALSO PUBLISHED AS: 20020129813
1 Status Updates

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A method for aerosolizing a liquid comprises providing an aerosol generator having a plate with a plurality of apertures and a piezoelectric element to vibrate the plate. Liquid is supplied to the plate, and the piezoelectric element is energized to vibrate the plate at an initial frequency. The energy level is adjusted to vibrate the plate at its instantaneous resonant frequency during aerosolization of the liquid.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
STAMFORD DEVICES LIMITEDDANGAN GALWAY6
AEROGEN, INC.BASEL1

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Behzadian, Kamran Sunnyvale, CA 8 153
Burnside, Rob Mountain View, CA 1 49
Klimowicz, Michael Los Altos, CA 13 358
Litherland, Craig Cupertino, CA 7 152

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (5)
4,628,890 Fuel atomizer 64 1984
5,186,164 Mist inhaler 124 1991
5,297,734 Ultrasonic vibrating device 81 1991
5,415,161 Intermittant demand aerosol control device 77 1993
5,533,497 Sidestream aerosol generator and method in variable positions 76 1995
 
MINNESOTA MINING AND MANUFACTURING COMPANY (5)
5,115,803 Aerosol actuator providing increased respirable fraction 65 1990
5,347,998 Breath actuated inhaler having an electromechanical priming mechanism 115 1992
5,487,378 Inhaler 174 1993
5,477,992 Metered-dose aerosol valves 46 1994
5,515,841 Inhaler 81 1994
 
ELKEM AS (1)
5,654,460 Method for production of aklylhalosilanes 44 1995
 
Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg (2)
5,080,649 Dual-compartment hypodermic syringe 116 1990
5,320,603 Hypodermic syringe for lyophilized medicament 99 1992
 
MEDEX, INC. (1)
5,186,166 Powder nebulizer apparatus and method of nebulization 85 1992
 
Lechler GmbH & Co., KG (1)
4,796,807 Ultrasonic atomizer for liquids 66 1988
 
IBM INFORMATION PRODUCTS CORPORATION, 55 RAILROAD AVENUE, GREENWICH, CT 06830 A CORP OF DE (1)
4,475,113 Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids 72 1983
 
NOVARTIS PHARMA AG (8)
5,164,740 High frequency printing mechanism 107 1991
5,458,135 Method and device for delivering aerosolized medicaments 246 1992
5,938,117 Methods and apparatus for dispensing liquids as an atomized spray 113 1995
5,654,007 Methods and system for processing dispersible fine powders 118 1995
5,586,550 Apparatus and methods for the delivery of therapeutic liquids to the respiratory system 120 1995
5,758,637 Liquid dispensing apparatus and methods 201 1996
6,085,740 Liquid dispensing apparatus and methods 186 1998
6,235,177 Method for the construction of an aperture plate for dispensing liquid droplets 60 1999
 
DISETRONIC AG (1)
5,515,842 Inhalation device 129 1994
 
BSH BOSCH UND SIEMENS HAUSGERÄTE GMBH (2)
4,334,531 Inhalator 101 1980
4,301,093 Atomizer for liquid 92 1980
 
Kraftwerk Union Aktiengesellschaft (1)
4,431,136 Slit nozzle and fast-acting shutoff valve 55 1981
 
HITACHI, LTD. (1)
4,865,006 Liquid atomizer 52 1988
 
HABLEY MEDICAL TECHNOLOGY CORPORATION (1)
5,435,282 Nebulizer 79 1994
 
DELAVAN CORPORATION WEST DES MOINES (1)
4,659,014 Ultrasonic spray nozzle and method 96 1985
 
ETHICON, INC. (1)
5,714,551 High strength, melt processable, lactide-rich, poly (lactide-co-p-dioxanone) copolymers 54 1996
 
MICRODOSE THERAPEUTX, INC. (2)
* 6,142,146 Inhalation device 71 1998
* 6,152,130 Inhalation device with acoustic control 83 1998
 
Piezo Electric Products, Inc. (2)
4,702,418 Aerosol dispenser 118 1985
4,753,579 Ultrasonic resonant device 75 1986
 
Toa Nenryo Kogyo Kabushiki Kaisha (1)
4,799,622 Ultrasonic atomizing apparatus 68 1987
 
CANON KABUSHIKI KAISHA (2)
4,368,476 Ink jet recording head 120 1980
* 5,788,819 Method for driving liquid, and method and apparatus for mixing and agitation employing the method 59 1997
 
TRANSPHARMA LTD (1)
* 6,328,033 Powder inhaler 76 1999
 
HEWLETT-PACKARD COMPANY (1)
4,336,544 Method and apparatus for drop-on-demand ink jet printing 72 1980
 
L'OREAL (2)
5,529,055 Piezoelectric nebulizing apparatus 62 1994
5,692,644 Container for storing at least two products, mixing these products, and dispensing the mixture thus obtained 76 1995
 
SIEMENS AKTIENGESELLSCHAFT (5)
4,539,575 Recorder operating with liquid drops and comprising elongates piezoelectric transducers rigidly connected at both ends with a jet orifice plate 97 1984
4,544,933 Apparatus and method for ink droplet ejection for a printer 52 1984
4,620,201 Magnetic driver ink jet 48 1986
4,888,516 Piezoelectrically excitable resonance system 56 1988
4,877,989 Ultrasonic pocket atomizer 231 1989
 
U.S. PHILIPS CORPORATION (1)
4,828,886 Method of applying small drop-shaped quantities of melted solder from a nozzle to surfaces to be wetted and device for carrying out the method 86 1987
 
BOEHRINGER INGELHEIM INTERNATIONAL GMBH (1)
4,261,512 Inhalation aerosol spray device 50 1980
 
The Board of Trustees of the University of Illinois (1)
* 6,060,128 Method of producing thin film and nanoparticle deposits using charges of alternating polarity 44 1999
 
SENSITRON, INC. (2)
5,157,372 Flexible potentiometer 70 1990
5,309,135 Flexible potentiometer in a horn control system 80 1993
 
WARNER-LAMBERT COMPANY (1)
4,268,460 Nebulizer 129 1980
 
RICOH COMPANY, LTD. (1)
4,591,883 Ink-jet printer head 56 1985
 
ARTE CORPORATION (1)
5,665,068 Dual chamber prefillable syringe 47 1995
 
SORIN BIOMEDICA S.P.A. (1)
5,139,016 Process and device for aerosol generation for pulmonary ventilation scintigraphy 69 1989
 
BIO-METRIC SYSTEM, INC. (1)
4,973,493 Method of improving the biocompatibility of solid surfaces 383 1987
 
N.V. ORGANON (1)
4,994,043 Two compartment syringe 66 1988
 
STAMFORD DEVICES LIMITED (2)
6,014,970 Methods and apparatus for storing chemical compounds in a portable inhaler 123 1998
6,205,999 Methods and apparatus for storing chemical compounds in a portable inhaler 70 1998
 
TRACOR HYDRONAUTICS (2)
4,389,071 Enhancing liquid jet erosion 73 1980
4,474,251 Enhancing liquid jet erosion 68 1981
 
DEVILBISS HEALTH CARE, INC. (1)
5,170,782 Medicament nebulizer with improved aerosol chamber 93 1991
 
SURMODICS IVD, INC. (2)
5,512,474 Cell culture support containing a cell adhesion factor and a positively-charged molecule 93 1994
5,707,818 Device and method for simultaneously performing multiple competitive immunoassays 65 1994
 
Mountain Medical Equipment, Inc. (1)
4,976,259 Ultrasonic nebulizer 96 1988
 
POLAROID CORPORATION (1)
4,550,325 Drop dispensing device 79 1984
 
THE TECHNOLOGY PARTNERSHIP PLC (1)
5,518,179 Fluid droplets production apparatus and method 132 1994
 
SEIKO EPSON CORPORATION (1)
5,063,396 Droplets jetting device 67 1990
 
SURMODICS, INC. (14)
4,722,906 Binding reagents and methods 222 1982
5,073,484 Quantitative analysis apparatus and method 164 1983
4,826,759 Field assay for ligands 160 1984
4,979,959 Biocompatible coating for solid surfaces 327 1989
5,002,582 Preparation of polymeric surfaces via covalently attaching polymers 253 1989
5,258,041 Method of biomolecule attachment to hydrophobic surfaces 128 1991
5,217,492 Biomolecule attachment to hydrophobic surfaces 165 1991
5,263,992 Biocompatible device with covalently bonded biocompatible agent 202 1991
5,654,162 Chemical analysis apparatus and method 98 1992
5,414,075 Restrained multifunctional reagent for surface modification 132 1992
5,512,329 Substrate surface preparation 105 1993
5,637,460 Restrained multifunctional reagent for surface modification 92 1994
5,563,056 Preparation of crosslinked matrices containing covalently immobilized chemical species and unbound releasable chemical species 156 1995
5,714,360 Photoactivatable water soluble cross-linking agents containing an onium group 119 1995
 
TDK Electronics Co., Ltd. (1)
4,474,326 Ultrasonic atomizing device 75 1982
 
TDK CORPORATION (4)
4,850,534 Ultrasonic wave nebulizer 107 1988
5,021,701 Piezoelectric vibrator mounting system for a nebulizer 65 1989
5,299,739 Ultrasonic wave nebulizer 78 1992
5,312,281 Ultrasonic wave nebulizer 82 1992
 
BOETTNER, MELISSA (1)
4,454,877 Portable nebulizer or mist producing device 66 1981
 
OMRON TATEISI ELECTRONICS CO. (2)
4,793,339 Ultrasonic atomizer and storage bottle and nozzle therefor 96 1988
4,790,479 Oscillating construction for an ultrasonic atomizer inhaler 110 1988
 
APTAR FRANCE SAS (1)
* 6,196,219 Liquid droplet spray device for an inhaler suitable for respiratory therapies 84 1998
 
MICROSPRAY DELTA S.P.A. (1)
5,431,155 Single-dose nasal dispenser for atomized liquid drugs 73 1993
 
PONWELL ENTERPRISES LIMITED, A BRITISH VIRGIN ISLANDS COMPANY, C/O BYRNE TRUST COMPANY LIMITED. (1)
* 6,196,218 Piezo inhaler 146 1999
 
HAHN, GARY S. (1)
5,893,515 Mist generator 58 1994
 
ETELA-HAMEEN KEUHKOVAMMAYHDISTYS R.Y. (1)
5,063,922 Ultrasonic atomizer 239 1989
 
WALLI, RICHARD A. (1)
4,408,719 Sonic liquid atomizer 59 1981
 
BATTELLE MEMORIAL INSTITUTE (5)
* 5,115,971 Nebulizer device 59 1988
* 5,511,726 Nebulizer device 180 1993
* 5,915,377 Dispensing device producing multiple comminutions of opposing polarities 81 1997
* 6,105,877 Dispensing device 65 1997
* 6,318,640 Dispensing device 71 2000
 
AT&T Bell Laboratories (1)
5,180,482 Thermal annealing of palladium alloys 43 1991
 
I.P.S. INDUSTRIE DES POUDRES SPHERIQUES S.A. (1)
5,198,157 Ultrasonic device for the continuous production of particles 71 1991
 
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (1)
5,744,515 Method and implantable article for promoting endothelialization 203 1996
 
XETEL CORPORATION (1)
5,452,711 Small form factor atomizer 64 1993
 
BABAEV, EILAZ P. (1)
5,076,266 Device for ultrasonic atomizing of liquid medium 73 1990
 
BECTON, DICKINSON AND COMPANY (1)
5,489,266 Syringe assembly and method for lyophilizing and reconstituting injectable medication 106 1994
 
FREEDOM MULTIMEDIA LLC (1)
5,086,785 Angular displacement sensors 148 1989
 
Dataproducts Corporation (1)
4,593,291 Method for operating an ink jet device to obtain high resolution printing 55 1984
 
YKK CORPORATION (1)
5,910,698 Method and apparatus for controlling piezoelectric vibration 33 1997
 
CAREFUSION 2200, INC. (1)
5,579,757 Anti-siphon flow restricter for a nebulizer 53 1994
 
Ing. C. Olivetti & C., S.p.A. (1)
4,546,361 Ink jet printing method and device 64 1983
 
MAQUET CRITICAL CARE AB (1)
* 6,032,665 Dosing device for adding an additive fluid to breathing gas in an anaesthesia machine or ventilator 35 1997
 
ARADIGM CORPORATION (3)
5,718,222 Disposable package for use in aerosolized delivery of drugs 110 1995
* 5,960,792 Device for aerosolized delivery of peptide drugs 182 1995
6,012,450 Intrapulmonary delivery of hematopoietic drug 145 1996
 
Hydronautics, Incorporated (1)
4,681,264 Enhancing liquid jet erosion 81 1984
 
KABI PHARMACIA AB (1)
4,968,299 Method and device for injection 137 1988
 
CONSORT MEDICAL PLC (3)
5,152,456 Dispensing apparatus having a perforate outlet member and a vibrating device 126 1990
5,261,601 Liquid dispensing apparatus having a vibrating perforate membrane 127 1992
6,062,212 Dispensing apparatus 70 1995
 
MATSUSHITA ELECTRIC WORKS, LTD. (1)
4,479,609 Liquid sprayer 74 1982
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (5)
4,465,234 Liquid atomizer including vibrator 92 1981
4,533,082 Piezoelectric oscillated nozzle 123 1982
4,605,167 Ultrasonic liquid ejecting apparatus 110 1983
4,530,464 Ultrasonic liquid ejecting unit and method for making same 74 1983
4,632,311 Atomizing apparatus employing a capacitive piezoelectric transducer 77 1983
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
COMEDICA INCORPORATED (3)
7,909,033 Breathing treatment apparatus 11 2007
8,051,854 Continuous high-frequency oscillation breathing treatment apparatus 4 2007
9,050,434 Lung therapy device 0 2008
 
RESPIRONICS RESPIRATORY DRUG DELIVERY (UK) LTD. (1)
* 8,261,738 Apparatus and method for maintaining consistency for aerosol drug delivery treatments 0 2008
 
HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (2)
7,819,115 Inhalers and methods of controlling airflow in inhalers 4 2004
7,380,550 Systems and methods for particle detection 6 2004
 
NOVARTIS AG (12)
7,946,291 Ventilation systems and methods employing aerosol generators 1 2004
* 8,616,195 Nebuliser for the production of aerosolized medication 3 2004
* 2005/0011,514 Nebuliser for the production of aerosolized medication 38 2004
7,267,121 Aerosol delivery apparatus and method for pressure-assisted breathing systems 18 2004
7,201,167 Method and composition for the treatment of lung surfactant deficiency or dysfunction 17 2005
7,971,588 Methods and systems for operating an aerosol generator 15 2005
7,771,642 Methods of making an apparatus for providing aerosol for medical treatment 2 2005
8,398,001 Aperture plate and methods for its construction and use 0 2006
8,561,604 Liquid dispensing apparatus and methods 0 2007
7,748,377 Methods and systems for operating an aerosol generator 13 2007
8,196,573 Methods and systems for operating an aerosol generator 9 2008
8,539,944 Devices and methods for nebulizing fluids for inhalation 0 2008
 
AEROSURGICAL LIMITED (1)
8,551,036 Insufflation system 0 2012
 
NEKTAR THERAPEUTICS (3)
7,600,511 Apparatus and methods for delivery of medicament to a respiratory system 22 2002
9,108,211 Vibration systems and methods 0 2006
8,555,874 Aerosolization device 1 2009
 
NOVARTIS PHARMA AG (14)
7,066,398 Aperture plate and methods for its construction and use 34 2001
7,360,536 Devices and methods for nebulizing fluids for inhalation 3 2003
7,040,549 Systems and methods for controlling fluid feed to an aerosol generator 15 2003
7,322,349 Apparatus and methods for the delivery of medicaments to the respiratory system 10 2003
7,174,888 Liquid dispensing apparatus and methods 11 2003
7,032,590 Fluid filled ampoules and methods for their use in aerosolizers 25 2004
6,978,941 Base isolated nebulizing device and methods 18 2004
7,290,541 Aerosol delivery apparatus and method for pressure-assisted breathing systems 10 2004
7,195,011 Convertible fluid feed system with comformable reservoir and methods 7 2004
7,331,339 Methods and systems for operating an aerosol generator 21 2004
7,677,467 Methods and devices for aerosolizing medicament 8 2005
7,104,463 Base isolated nebulizing device and methods 14 2005
7,628,339 Systems and methods for controlling fluid feed to an aerosol generator 13 2006
8,336,545 Methods and systems for operating an aerosol generator 7 2007
 
APTAR FRANCE SAS (1)
7,861,943 Adaptive piezoelectric actuator control system 2 2008
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (2)
* 8,602,023 Methods, devices and formulations for targeted endobronchial therapy 0 2005
8,733,350 Medthods, devices and formulations for targeted endobronchial therapy 0 2009
 
EYENOVIA, INC. (3)
9,087,145 Ophthalmic drug delivery 0 2011
8,733,935 Method and system for performing remote treatment and monitoring 0 2011
8,684,980 Drop generating device 0 2011
 
FUJI XEROX CO., LTD. (1)
* 7,753,497 Piezoelectric element, liquid droplet ejection head, and liquid droplet ejection apparatus 1 2005
 
STAMFORD DEVICES LIMITED (1)
* 2011/0178,458 INSUFFLATION OF BODY CAVITIES 0 2011
 
MICRODOSE THERAPEUTX, INC. (4)
* 8,474,452 Directional flow sensor inhaler 0 2005
* 2005/0183,725 Directional flow sensor inhaler 11 2005
8,763,606 Rotary cassette system for dry powder inhaler 1 2010
* 8,985,101 Method and device for clamping a blister within a dry powder inhaler 0 2013
 
OPTIMYST SYSTEMS, INC. (5)
7,883,031 Ophthalmic drug delivery system 7 2004
* 2004/0256,487 Ophthalmic drug delivery system 40 2004
8,545,463 Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device 1 2007
8,012,136 Ophthalmic fluid delivery device and method of operation 6 2007
8,936,021 Ophthalmic fluid delivery system 0 2008
* Cited By Examiner