Therapeutic agents and methods of use thereof for the modulation of angiogenesis

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United States of America Patent

PATENT NO 6548477
SERIAL NO

09704251

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Abstract

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The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e.g., cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMITHKLINE LLC251 LITTLE FALLS DRIVE WILMINGTON DE 19808

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Birktoft, Jens J New York, NY 1 86
Cook, Charles Michael Mendham, NJ 14 240
Lee, Lily Edison, NJ 17 315
Olson, Gary L Mountainside, NJ 56 974
Self, Christopher West Caldwell, NJ 25 424

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