Bi-and trispecific antibodies for the induction of anti-tumor immunity
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United States of America Patent
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Apr 22, 2003
Grant Date -
May 2, 2002
app pub date -
Sep 3, 1997
filing date -
Sep 3, 1996
priority date (Note) -
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Abstract
According to the invention, a method is provided wherein intact bispecific or trispecific antibodies which at the same time bind to the T cell receptor complex of a T cell, to tumor-associated antigens on a tumor cell, and, via the Fc portion of the bispecific antibody, to Fc receptor-positive cells are used for the induction of an anti-tumour immunity in humans and animals.
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