Methods for enhancing binding interactions between members of specific binding pairs

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United States of America Patent

PATENT NO 6551843
SERIAL NO

09240939

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Abstract

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Disclosed is a method that improves the efficiency of reactions between specific binding pairs. By translating one member of the pair through a suspension of the second member, or across a surface to which the second member is immobilized, collision and binding frequencies are greatly increased. The resulting increased binding frequency allows for reduced incubation times and lower incubation temperatures. The enhanced collisions are advantageous for both molecular reactions, in which mixing is not always effective, and cellular reactions, in which the cells may be damaged by mixing.

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Patent Owner(s)

Patent OwnerAddress
VERIDEX LLC1001 US ROUTE 202 RARITAN NJ 08869

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liberti, Paul Hundingdon Valley, PA 1 39
Rao, Galla Chandra Princeton, NJ 31 1454
Terstappen, Leon Huntingdon Valley, PA 1 39

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