Transgenic mice comprising CD45 knockout

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United States of America Patent

PATENT NO 6552246
SERIAL NO

08451318

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A mammal lacking expression of particular CD45 isoform in certain cells of the immune system is provided. The mammal may optionally contain a transgene encoding the CD45RO isoform. Also provided are methods of using these mammals.

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Patent Owner(s)

Patent OwnerAddress
ONTARIO CANCER INSTITUTETORONTO ONTARIO M4X 1K9

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mak, Tak Wah Toronto, CA 11 45
Penninger, Josef Martin Toronto, CA 3 49

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