O-glucosylated benzamide SGLT2 inhibitors and method
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United States of America Patent
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Apr 29, 2003
Grant Date -
May 2, 2002
app pub date -
Feb 23, 2001
filing date -
Mar 30, 2000
priority date (Note) -
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Abstract
SGLT2 inhibiting compounds are provided having the formula ##STR1## wherein n is 0, 1 or 2; A is ##STR2## or heteroaryl which may contain 1 to 4 heteroatoms in the ring which may be selected from N, O, S, SO, and/or SO.sub.2, bearing substituents R.sup.3 and R.sup.4 ; and R.sup.1 to R.sup.4 are as defined herein. A method is also provided for treating diabetes and related diseases employing an SGLT2 inhibiting amount of the above compound alone or in combination with one, two or more other antidiabetic agents and/or one, two or more hypolipidemic agents.
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